Emerson Harkin

contact-739please-dont-spam-me@efharkin.com at efharkin.com

0000-0003-0698-5894 Emerson F. Harkin efharkin efharkin_ efharkin

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Education

Honours and awards

Research contributions

Publications

1. Harkin EF, Nasrallah G, Le François B, and Albert PR. "Transcriptional regulation of the human 5-HT1A receptor gene by lithium: Role of Deaf1 and GSK3β." International Journal of Molecular Sciences, 24, 2023. doi: 10.3390/ijms242115620
2. Harkin EF, Grossman CD, Cohen JY, Béïque J-C, and Naud R. "Serotonin predictively encodes value." bioRxiv, 2023. doi: 10.1101/2023.09.19.558526
3. Harkin EF, Lynn MB, Payeur A, Boucher JF, Caya-Bissonnette L, Cyr D, Stewart C, Longtin A, Naud R*, and Béïque J-C*. "Temporal derivative computation in the dorsal raphe network revealed by an experimentally-driven augmented integrate-and-fire modeling framework." eLife, 12, 2023. doi: 10.7554/eLife.72951
4. Lynn MB, Geddes S, Chahrour M, Maillé S, Harkin E, Harvey-Girard É, Haj-Dahmane S, Naud R, and Béïque J-C. "A slow 5-HT_1AR-mediated recurrent inhibitory network in raphe computes contextual value through synaptic facilitation." bioRxiv, 2022. doi: 10.1101/2022.08.31.506056
5. Harkin EF*, Shen PR*, Goel A, Richards BA*, and Naud R*. "Parallel and recurrent cascade models as a unifying force for understanding subcellular computation." Neuroscience, 489:200-215, 2022. doi: 10.1016/j.neuroscience.2021.07.026
6. Lee C, Harkin E, Yin X, Naud R, and Chen S. "Cell-type-specific responses to associative learning in the primary motor cortex." eLife, 2022. doi: 10.7554/eLife.72549
7. Mazhar H, Harkin E, Foster B, and Harris C. "Complementary and alternative medicine use in pediatric ADHD." Current Developmental Disorders Reports, 3(1):15-24, 2016.

Textbook chapters

1. Harkin EF, Béïque J-C, and Naud R. "A user's guide to generalized integrate-and-fire models." Computational Modelling of the Brain, eds. Giugliano, Negrello, and Linaro, Springer, 69-89, 2022. doi: 10.1007/978-3-030-89439-9_3

Conference abstracts

1. Harkin EF, Grossman CD, Cohen JY, Béïque J-C, and Naud R. "A prospective code for value in the serotonin system." Invited talk as part of the Theoretical Sciences Visiting Program at the Okinawa Institute of Science and Technology, Okinawa, Japan, Jul 2024.
2. Harkin EF, Grossman CD, Cohen JY, Béïque J-C, and Naud R. "Serotonin predictively encodes value." Poster presented at COSYNE, Lisbon, Portugal, Mar 2024.
3. Harkin EF, Béïque J-C, and Naud R. "Serotonin predictively encodes value." Talk at Neuroscience, Washington, D.C., U.S.A., Nov 2023.
4. Harkin EF, Payeur A, Lynn MB, Boucher J-F, Caya-Bissonnette L, Cyr D, Stewart C, Longtin A, Naud R*, and Béïque J-C*. "Temporal derivative computation in the dorsal raphe network revealed by an experimentally-driven augmented integrate-and-fire modeling framework." Poster presented at Neuroscience, San Diego, U.S.A., Nov 2022.
5. Harkin EF, Payeur A, Lynn MB, Boucher J-F, Caya-Bissonnette L, Cyr D, Stewart C, Longtin A, Béïque J-C*, and Naud R*. "Temporal derivative computation in the dorsal raphe network revealed by an experimentally-driven augmented integrate-and-fire modeling framework." Poster presented at Bernstein Conference, virtual, Sep 2021. doi: 10.12751/nncn.bc2021.p083
6. Lynn M, Geddes SD, Chahrour M, Maillé S, Harkin E, Harvey-Girard É, Haj-Dahmane S, Naud R, and Béïque. "Dynamic filtering of habenulo-raphe inputs by a serotonergic reccurent inhibitory network acting over behavioural timescales." Poster presented by M Lynn at Neuroscience, virtual, Sep 2021.
7. Harkin E, Payeur A, Boucher J-F, Caya-Bissonnette L, Cyr D, Longtin A, Lynn M, Stewart C, Naud R*, and Béïque J-C*. "From single neurons to networks in the dorsal raphe nucleus." Poster presented at COSYNE, virtual, Feb 2021.
8. Harkin E, Payeur A, Boucher J-F, Caya-Bissonnette L, Cyr D, Longtin A, Lynn M, Stewart C, Béïque J-C*, and Naud R*. "Multiple mechanisms of gain modulation in the serotonin system." Talk presented at Canadian Computational Neuroscience Spotlight, virtual, Jun 2020.
9. Harkin E, Payeur A, Boucher J-F, Caya-Bissonnette L, Cyr D, Longtin A, Lynn M, Stewart C, Béïque J-C*, and Naud R*. "Multiple mechanisms of gain modulation in the serotonin system." Talk presented at Neuromatch 1.0, virtual, May 2020.
10. Harkin E, Payeur A, Lynn M, Boucher J-F, Longtin A, Naud R*, and Béïque J-C*. "Multiple mechanisms of gain modulation in the serotonin system." Poster accepted to Canadian Association for Neuroscience 14^th Annual Meeting, Montréal, Canada, May 2020.^†
11. Lynn M, Geddes S, Chahrour M, Maillé S, Harkin E, Haj-Dahmane S, Naud R, and Béïque J-C. "A recurrent network motif in the dorsal raphe nucleus supports an operational classification of habenula inputs." Poster accepted to Canadian Association for Neuroscience 14^th Annual Meeting, Montréal, Canada, May 2020.^†
12. Lynn M, Geddes S, Chahrour M, Maillé S, Harkin E, Haj-Dahmane S, Naud R, and Béïque J-C. "A recurrent network motif in the dorsal raphe nucleus supports an operational classification of habenula inputs." Poster presented by M Lynn at Canadian Association for Neuroscience 13^th Annual Meeting, Toronto, Canada, May 2019.
13. Harkin E, Lynn M, Payeur A, Longtin A, Naud R, and Béïque J-C. "Non-uniform subthreshold dynamics and integrative features in dorsal raphe neurons." Poster presented at Canadian Association for Neuroscience 12^th Annual Meeting, Vancouver, Canada, May 2018.
14. Harkin E, Cardin V, and Albert P. "Transcriptional regulation of the serotonin 1A receptor by lithium: roles of glycogen synthase kinase 3β and Deaf-1." Poster presented at Ottawa-Carleton Institute of Biology Symposium, Ottawa, Canada, 2016.

1. Equal contribution.
2. Abstract accepted, but in-person conference cancelled due to COVID.

Mentorship

Service